This fact sheet provides a useful outline of pharmacodynamic capabilities at MAC.
The application of pharmacodynamic assessments in both healthy volunteers and patients can be hugely beneficial as part of the early drug development process. The use of experimental models, where symptoms of a particular disease state are induced under controlled conditions, allow putative efficacy of compounds to be investigated in a “clean” manner. In addition to models, a whole range of pharmacodynamic techniques can be utilised to help paint a clearer picture about the activity of a drug.
